Gemoragik isitma qo'zg'atuvchilari patagenezi diagnostik tahlili
Kalit so'zlar:
Gemoragik isitma, viruslar, patogenez, endoteliy, gemorragik sindrom, PCR diagnostika, immun javob, sitokinlarAnnotatsiya
Gemoragik isitmalar virusli etiologiyaga ega og'ir yuqumli kasalliklar guruhiga kiradi. Ularning qo'zg'atuvchilari organizmga kirgach, endotelial hujayralarga zarar yetkazadi, tomirlar o'tkazuvchanligini oshiradi va gemorragik sindrom rivojlanishiga olib keladi. Patogenezida virus replikatsiyasi, immun javobning disbalansi hamda sitokin ―bo'roni‖ muhim o'rin tutadi. Kasallikning klinik ko'rinishlari gemorragiyalar, intoksikatsiya va ko'p a‘zoli yetishmovchilik bilan namoyon bo'ladi. Diagnostik tahlilda laborator, serologik va molekulyar usullar (PCR) asosiy ahamiyatga ega. Erta tashxis qo'yish kasallik oqibatini yaxshilashda muhim rol o'ynaydi.
Foydalanilgan adabiyotlar
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