Burutselyoz kasalligi patogenezi va labarator diagnostik tahlili
Keywords:
Brucellosis, Brucella, zoonosis, macrophage, granuloma, serological tests, ELISA, PCR, chronic infectionAbstract
Brucellosis is a zoonotic infectious disease caused by bacteria of the genus Brucella, transmitted to humans through infected animals and their products. In pathogenesis, the ability of Brucella to survive inside macrophages and spread through the lymphatic and reticuloendothelial systems plays a key role, leading to chronic inflammation. Clinically, it is characterized by prolonged fever, intoxication, and multiorgan involvement. The main diagnostic methods include serological tests (Wright, Rose Bengal, ELISA) and molecular techniques (PCR). Early diagnosis is essential for reducing complications.
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