JIGAR SIRROZI KASALLIGI BILAN BEMORLARDA SILIBININNING SAMARADORLIGINI O'RGANISH VA BAHOLASH
Kalit so'zlar:
jigar sirrozi, silibinin, silymarin, gepatositlar, antifibrotik ta'sir, antioksidant, klinik samaradorlik, jigar funksiyasiAnnotatsiya
Ushbu ilmiy maqolada jigar sirrozi bilan kasallangan bemorlarda silibininning (silymarin tarkibiy qismi) klinik samaradorligi, xavfsizligi va terapevtik ahamiyati kompleks tahlil qilingan. Tadqiqotda silibininning antifibrotik, antioksidant, membrana-stabilizatsion va regenerativ ta'siri, uning jigar funksional ko'rsatkichlariga, hayot sifati va kasallik prognoziga ta'siri o'rganilgan. Maqolada randomizatsiyalangan klinik tadqiqotlar natijalari, meta-tahlillar va xalqaro klinik qo'llanmalar ma'lumotlari asosida silibininning jigar sirrozida qo'llanilishining ilmiy asoslari yoritilgan. Natijalar shuni ko'rsatadiki, silibininni standart terapiya bilan kombinatsiyalashgan holda qo'llash jigar fermentlari darajasini normallashtirish, fibroz progresiyasini sekinlashtirish va bemorlarning klinik holatini yaxshilashda samarali vosita hisoblanadi.
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